1.Be responsible for formulating translational medicine strategies and plans in the field of chronic diseases such as cardiovascular and metabolic diseases, and promoting the smooth transformation of candidate drugs from preclinical research to the clinical development stage.
2. Lead or participate in the preclinical and early clinical research design of small nucleic acid drugs and other related drugs in the field of cardiovascular and metabolic diseases, including the formulation of clinical trial protocols, the selection and validation of biomarkers, etc.
3. Deeply interpret preclinical research data and clinical data to provide medical and clinical pharmacological basis for drug development decisions and solve translational medicine-related problems in the development process.
4. Work closely with cross-departmental teams such as preclinical research teams, clinical development teams, and medical affairs teams to ensure that translational medicine work is advanced in tandem with the overall R&D process.
5. Track the latest research progress and clinical needs in the fields of cardiovascular and metabolic diseases as well as small nucleic acid drugs, and provide suggestions for the company's R&D pipeline layout and project priority setting.
6. Establish and maintain cooperative relationships with external academic institutions, clinical research institutions and experts, and carry out cooperative research related to translational medicine.
7. Lead the translational medicine team, be responsible for the recruitment, training, performance management and development planning of team members, and enhance the overall professional capabilities and work efficiency of the team.
Job Requirements
1. Educational Background: Master's degree or above in medicine, clinical pharmacology or related fields, with a doctoral degree preferred. Those with relevant clinical training experience (such as standardized training for resident physicians) are preferred.
2. Work Experience:
At least 10 years of relevant working experience, with at least 7 years focused on cardiovascular and metabolic diseases. Possessing rich team management experience and successfully leading multiple translational medicine projects from early research and development to clinical stages.
1. Professional Background: Familiar with the pathophysiological mechanisms, clinical diagnosis and treatment norms, and unmet medical needs of cardiovascular and metabolic diseases. Those with experience in small nucleic acid drug research and development projects are preferred. Those familiar with the mechanism of action, pharmacokinetics, toxicology and clinical development characteristics of small nucleic acid drugs are even better.
2. Professional Skills: Possessing solid knowledge in medicine and clinical pharmacology, capable of independently designing preclinical translational research protocols and early clinical trial protocols. Have experience in the discovery, validation and application of biomarkers in clinical research. Possessing excellent data analysis skills and scientific research thinking, capable of extracting valuable information from complex data.
3. Comprehensive quality: Possess excellent communication and coordination skills as well as a spirit of teamwork, and be capable of effectively promoting cross-departmental cooperation. Possess strong leadership skills, project management capabilities and problem-solving abilities. Possessing an innovative spirit and a strong sense of responsibility, one can withstand certain work pressure.
4. Language proficiency: Possess excellent skills in listening, speaking, reading and writing in both Chinese and English, and be proficient in reading and writing English professional literature and research reports.